NEWS: Our manuscript on Unison was accepted to the 2009 Pacific Symposium on Biocomputing. The slides will appear there soon.
Unison in a Nutshell
Welcome to Unison

Unison is a compendium of protein sequences and extensive precomputed predictions. Integration of these and other data within Unison enables holistic mining of sequences based on protein features, analysis of individual and sets of sequences, and refinement of hypotheses regarding the composition of protein families.

Some uses of Unison:

Analysis of an Individual Sequence
Once you specify a sequence, you can get a gene/protein summary, database cross-references, precomputed features, structures and structural models with SNPs, and lots more.

Enter a sequence, sequence alias, md5 checksum:
An alias may be an accession or identifer from any database contained in Unison.
e.g., TNFA_HUMAN, P01375, NP_000585.2, IPI00001671.1, 60ada54e69e411bcf6b08e9dacff7a48


Feature-Based Mining
Unison excels at mining based on precomputed sequences features. You may search for sequences by specifying features, exploring curated models and sequence sets, or browsing predefined, dynamic queries.

Tools
Unison provides two web tools that are intended for users with high-throughput experimental data. BabelFish translates a list of protein aliases protein aliases (accessions, identifiers, or checksums) into aliases for several target databases based on sequence identity. AliAn provides a annotations, domains, locus, GO and other annotations for a list of protein aliases.